USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: LTOR2_HUMAN USC-OGP 2-DE database:  LTOR2_HUMAN LTOR2_HUMAN General information about the entry View entry in simple text format Entry name LTOR2_HUMAN Primary accession number Q9Y2Q5 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ragulator complex protein LAMTOR2; AltName: Full=Endosomal adaptor protein p14; AltName: Full=Late endosomal/lysosomal Mp1-interacting protein; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; AltName: Full=Mitogen-activated protein-binding protein-interacting protein; Short=MAPBP-interacting protein; AltName: Full=Roadblock domain-containing protein 3;. Gene name Name=LAMTOR2 Synonyms=MAPBPIP, ROBLD3 ORFNames=HSPC003 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0259: pI=5.00; Mw=14626 Cross-references UniProtKB/Swiss-Prot Q9Y2Q5; LTOR2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LTOR2_HUMAN Primary accession number Q9Y2Q5 Secondary accession number(s) Q5VY97 Q5VY98 Q5VY99 Sequence was last modified on  November 1, 1999 (version 1) Annotations were last modified on  March 15, 2017 (version 141) Name and origin of the protein Description RecName: Full=Ragulator complex protein LAMTOR2; AltName: Full=Endosomal adaptor protein p14; AltName: Full=Late endosomal/lysosomal Mp1-interacting protein; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; AltName: Full=Mitogen-activated protein-binding protein-interacting protein; Short=MAPBP-interacting protein; AltName: Full=Roadblock domain-containing protein 3; Gene name Name=LAMTOR2 Synonyms=MAPBPIP, ROBLD3 ORFNames=HSPC003 Encoded on Name=LAMTOR2; Synonyms=MAPBPIP, ROBLD3; ORFNames=HSPC003 Keywords Alternative splicing; Complete proteome; Endosome; Lysosome; Membrane; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF070659; AAD20965.1; -; mRNA EMBL AK307086; -; NOT_ANNOTATED_CDS; mRNA EMBL AL355388; CAH72635.1; -; Genomic_DNA EMBL AL355388; CAH72636.1; -; Genomic_DNA EMBL AL355388; CAH72637.1; -; Genomic_DNA EMBL BC024190; AAH24190.1; -; mRNA CCDS CCDS1128.1; -. [Q9Y2Q5-1]; . CCDS CCDS44243.1; -. [Q9Y2Q5-3]; . RefSeq NP_001138736.1; NM_001145264.1. [Q9Y2Q5-3]; . RefSeq NP_054736.1; NM_014017.3. [Q9Y2Q5-1]; . UniGene Hs.632483; -; . ProteinModelPortal Q9Y2Q5; -; . BioGrid 118783; 21; . DIP DIP-57000N; -; . IntAct Q9Y2Q5; 13; . MINT MINT-5003178; -; . STRING 9606.ENSP00000357288; -; . iPTMnet Q9Y2Q5; -; . PhosphoSitePlus Q9Y2Q5; -; . BioMuta LAMTOR2; -; . DMDM 12585246; -; . OGP Q9Y2Q5; -; . EPD Q9Y2Q5; -; . PaxDb Q9Y2Q5; -; . PeptideAtlas Q9Y2Q5; -; . PRIDE Q9Y2Q5; -; . TopDownProteomics Q9Y2Q5-1; -. [Q9Y2Q5-1]; . TopDownProteomics Q9Y2Q5-2; -. [Q9Y2Q5-2]; . TopDownProteomics Q9Y2Q5-3; -. [Q9Y2Q5-3]; . DNASU 28956; -; . Ensembl ENST00000368302; ENSP00000357285; ENSG00000116586. [Q9Y2Q5-2]; . Ensembl ENST00000368304; ENSP00000357287; ENSG00000116586. [Q9Y2Q5-3]; . Ensembl ENST00000368305; ENSP00000357288; ENSG00000116586. [Q9Y2Q5-1]; . GeneID 28956; -; . KEGG hsa:28956; -; . UCSC uc001fnb.4; human. [Q9Y2Q5-1]; . CTD 28956; -; . DisGeNET 28956; -; . GeneCards LAMTOR2; -; . HGNC HGNC:29796; LAMTOR2; . HPA HPA004126; -; . MalaCards LAMTOR2; -; . MIM 610389; gene; . MIM 610798; phenotype; . neXtProt NX_Q9Y2Q5; -; . OpenTargets ENSG00000116586; -; . Orphanet 90023; Primary immunodeficiency syndrome due to p14 deficiency; . PharmGKB PA164725527; -; . eggNOG KOG4107; Eukaryota; . eggNOG ENOG4111GWH; LUCA; . GeneTree ENSGT00390000006100; -; . HOGENOM HOG000007645; -; . HOVERGEN HBG004518; -; . InParanoid Q9Y2Q5; -; . KO K20398; -; . OMA CECGHVA; -; . OrthoDB EOG091G0W0V; -; . PhylomeDB Q9Y2Q5; -; . TreeFam TF313929; -; . Reactome R-HSA-1632852; Macroautophagy; . Reactome R-HSA-165159; mTOR signalling; . Reactome R-HSA-166208; mTORC1-mediated signalling; . Reactome R-HSA-380972; Energy dependent regulation of mTOR by LKB1-AMPK; . Reactome R-HSA-5628897; TP53 Regulates Metabolic Genes; . Reactome R-HSA-5674135; MAP2K and MAPK activation; . Reactome R-HSA-6798695; Neutrophil degranulation; . SIGNOR Q9Y2Q5; -; . ChiTaRS LAMTOR2; human; . GenomeRNAi 28956; -; . PRO PR:Q9Y2Q5; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000116586; -; . Genevisible Q9Y2Q5; HS; . GO GO:0010008; C:endosome membrane; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005770; C:late endosome; ISS:UniProtKB; . GO GO:0005765; C:lysosomal membrane; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0071986; C:Ragulator complex; IDA:UniProtKB; . GO GO:0035579; C:specific granule membrane; TAS:Reactome; . GO GO:0070821; C:tertiary granule membrane; TAS:Reactome; . GO GO:0000186; P:activation of MAPKK activity; IEA:Ensembl; . GO GO:0007050; P:cell cycle arrest; TAS:Reactome; . GO GO:0016049; P:cell growth; IMP:UniProtKB; . GO GO:0034613; P:cellular protein localization; IMP:UniProtKB; . GO GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB; . GO GO:0016236; P:macroautophagy; TAS:Reactome; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0043547; P:positive regulation of GTPase activity; IEA:GOC; . GO GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB; . InterPro IPR004942; Roadblock/LAMTOR2_dom; . Pfam PF03259; Robl_LC7; 1; . SMART SM00960; Robl_LC7; 1; .

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